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https://d1y502jg6fpugt.cloudfront.net/25425/archive/files/4138972b88fa1258afbb22e6bb6644c3.pdf?Expires=1712793600&Signature=lKLm4TM0KHsl9o84E9Av5BViw2TNgLg46-00EOLQDzSxeKOdrmEo-1Ls2UiwPIhWMGYfN-pOkr5L7DjyeHamai8k7UwOLR2nkFQVTOqLxC7exc7mXpxsrle3qSUIGbjMXLubwbcqr8oPdjhvxlirbcQhRH6D2w%7EobgeI%7EimbwuSFCYoApbNzmGpXYtnAcmO23ribwiAbPBUa3zLlLVodxEoAYXpetTEUVuQVkSb8-DzKKNby6soxc0AO8ELPXIUZp9JRHaAWz-V%7E1IgBJANS2xoOE9WpJNEH2rhgYSADi-hxqzsx%7ElngOj0VuNVYysICIxlX7zpf1vPWfeVdvp01jA__&Key-Pair-Id=K6UGZS9ZTDSZM
056e1f96a030108703a4fa1c38748661
Website
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<a href="https://www.trivedieffect.com/science/spectroscopic-characterization-of-chloramphenicol-and-tetracycline-an-impact-of-biofield-treatment">https://www.trivedieffect.com/science/spectroscopic-characterization-of-chloramphenicol-and-tetracycline-an-impact-of-biofield-treatment</a>
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Title
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Spectroscopic Characterization of Chloramphenicol and Tetracycline: An Impact of Biofield Treatment
Subject
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Pharmaceuticals
Description
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<p style="text-align:justify;">Objective: Chloramphenicol and tetracycline are broad-spectrum antibiotics and widely used against variety of microbial infections. Nowadays, several microbes have acquired resistance to chloramphenicol and tetracycline. The present study was aimed to evaluate the impact of biofield treatment for spectroscopic characterization of chloramphenicol and tetracycline using FT-IR and UV-Vis spectroscopy. Methods: The study was performed in two groups (control and treatment) of each antibiotic. The control groups remained as untreated, and biofield treatment was given to treatment groups. Results: FT-IR spectrum of treated chloramphenicol exhibited the decrease in wavenumber of NO2 from 1521 cm-1 to 1512 cm-1 and increase in wavenumber of C=O from 1681 cm-1 to 1694 cm-1 in acylamino group. It may be due to increase of conjugation effect in NO2 group, and increased force constant of C=O bond. As a result, stability of both NO2 and C=O groups might be increased in treated sample as compared to control. FT-IR spectrum of treated tetracycline showed the downstream shifting of aromatic C-H stretching from 3085-3024 cm-1 to 3064-3003 cm-1 and C=C stretching from 1648-1582 cm-1 to 1622-1569 cm-1 and up shifting of C-N stretching from 965 cm-1 to 995 cm-1. It may be due to enhanced conjugation effect in tetracycline, and increased force constant of C-N (CH3) bond of tetracycline as compared to control. The results indicated the enhanced stability of treated tetracycline as compared to control. UV-Vis spectra of biofield treated chloramphenicol and tetracycline showed the similar lambda max (λmax) to their respective control. It revealed that the chromophore groups of both antibiotics remained same as control after the biofield treatment. Conclusion: Based on FT-IR spectroscopic data, it is speculated that due to increase in bond strength and conjugation effect after biofield treatment, the chemical stability of both the drugs might be increased as compared to control.</p>
Creator
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Mahendra Kumar Trivedi, Shrikant Patil, Harish Shettigar, Khemraj Bairwa, Snehasis Jana
Source
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<a href="https://www.omicsonline.org/open-access/spectroscopic-characterization-of-chloramphenicol-and-tetracycline-an-impact-of-biofield-treatment-2153-2435-1000395.php?aid=57600+">https://www.omicsonline.org/open-access/spectroscopic-characterization-of-chloramphenicol-and-tetracycline-an-impact-of-biofield-treatment-2153-2435-1000395.php?aid=57600+</a>
Publisher
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Omics Publishing Group
Date
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July 24, 2015
Language
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English
Type
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Journal Article
Identifier
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10.4172/2153-2435.1000395
Biofield Treatment
Chloramphenicol
Fourier transform infrared spectroscopy
Tetracycline
Ultraviolet spectroscopy